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  /  Juan Bueren

Juan Bueren

Country

Spain

Institution

CIEMAT, National Institute of Rare Diseases (CIBERER) and Fundación Jiménez Díaz. Madrid. Spain

Biography

Prof Bueren is Director of the Hematopoietic Innovative Therapies Division at CIEMAT and the Biomedical Network Centre for Research on Rare Diseases (CIBERER) and co-ordinator of the Advanced Therapies Unit of Fundación Jiménez Díaz/CIEMAT.
Author of 150 papers in indexed international journals on topics related with gene therapy, hematopoietic stem cells and cell reprogramming. In 2011 received the Distinguished Service Award from the Fanconi Anemia Research Fund.
Prof Bueren is former President of the Spanish Society for Gene and Cell Therapy (2011-2013) and current member of the Board of the European Society for Gene and Cell Therapy (2014-present), the Hematologic and Immunologic Gene and Cell Therapy Committee ASGCT (2015-present) and the Rector Council of the Spanish Agency of Medicines.

References

Ángel Raya, Ignasi Rodríguez-Pizà, Guillermo Guenechea, Rita Vassena, Susana Navarro, María José Barrero, Antonella Consiglio, Paula Río, Eduard Sleep, Gustavo Tiscornia, Elena Garreta, Trond Aasen, Anna Veiga, Inder M. Verma, Juan Bueren & Juan Carlos Izpisúa Belmonte. Generation of disease-free hematopoietic progenitors from Fanconi anemia-specific induced pluripotent stem cells. Nature. 460: 53-59 (2009).

Rio P, Baños R, Lombardo A, Quintana-Bustamante O, Alvarez L, Garate Z, Genovese P, Almarza E, Valeri A, Díez B, Navarro S, Torres Y, Trujillo JP, Murillas R, Segovia JC, Samper E, Surralles J, Gregory PD, Holmes MC, Naldini L, Bueren JA. Targeted gene therapy and cell reprogramming in Fanconi anemia. EMBO Mol Med. 6:835-48 (2014)

Río P, Navarro S, Guenechea G, Sánchez-Domínguez R, Lamana ML, Yañez R, Casado JA, Mehta PA, Pujol MR, Surrallés J, Charrier S, Galy A, Segovia JC, Díaz de Heredia C, Sevilla J, Bueren J. Engraftment and in vivo proliferation advantage of gene corrected mobilized CD34+ cells from Fanconi anemia patients. Blood. 130:1535-1542 (2017)

B Diez, P Genovese, FJ Roman-Rodriguez, L Alvarez, G Schiroli, L Ugalde, S Rodríguez-Perales, J Sevilla, C Díaz de Heredia, MC Holmes, A Lombardo, Li Naldini, JA Bueren* and P Rio*. Therapeutic Gene Editing in CD34+ Hematopoietic Progenitors from Fanconi Anemia Patients. EMBO Mol Med. 9:1574-1588. (2017)

Job position

Director of the Hematopoietic Innovative Therapies Division